Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 202-918-9 | CAS number: 101-14-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Guidance on Safe Use
Administrative data
First-aid measures
Swallowing:
Do not induce vomiting. Rinse mouth with water. Give two glasses of milk or water at once. Obtain medical attention in all cases.
Inhalation:
Remove to fresh air. If breathing is difficult, administer oxygen. Obtain medical attention if symptoms persist.
Skin contact:
Wash skin with soap and water. Obtain medical attention if irritation persists.
Eye contact:
Immediately flush eyes with water and continue washing for at least 15 minutes. Obtain medical attention if discomfort persists
Fire-fighting measures
Hazardous combustion products:
Irritating fumes.
Oxides of carbon.
Oxides of nitrogen.
Hydrogen cyanide.
Hydrogen chloride.
o-Chloroaniline upon heating.
Special fire fighting procedures:
Do not discharge extinguishing waters into streams, rivers and lakes.
Special protective equipment for firefighters:
Body covering protective clothing, full "turn-out" gear.
Self-contained breathing apparatus.
Extinguishing media:
Suitable:
Large fires:
- alcohol-type foam or universal-type foams
Small fires:
- CO2
- dry chemical
- water spray
Unsuitable:
- water jets
Accidental release measures
Personal precautions:
Evacuate unnecessary personnel.
Avoid all contact with material.
Wear suitable protective equipment.
Environmental precaution:
Prevent from entering sewer system, surface water or soil.
Methods for cleaning up:
Sweep up and collect in a suitable container for disposal.
Avoid dust formation.
Observe government regulations.
Handling and storage
HANDLING
Handling precautions:
Wear recommended personal protection equipment.
Warn personnel about the dangers of the product.
Keep container tightly closed.
Avoid dispersion of dust to reduce fire and explosion potential.
Other precautions:
Avoid contact with moisture and prolonged exposure to temperatures above 140°F (60°C).
Purge containers with dry nitrogen before resealing.
Do not use spot heating devices such as band heaters or torches.
Make sure contents are completely liquid and uniform before using.
(SEE TECHNICAL BULLETIN FOR ADDITIONAL DETAILS)
STORAGE
Storage requirements:
Store in a cool, dry place.
Further information on storage:
4,4'-Methylen-bis(2-chloranilin) (MOCA) is subject to EU-Directive 96/82/EC and amendments on the control of major-accident hazards involving dangerous substances (The Seveso Directive).
Transport information
Land transport (UN RTDG/ADR/RID)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- Environmentally hazardous substance, solid, n.o.s.
- Chemical name:
- 4,4'-Methylene bis-{2-Chloroaniline}
- Language:
- English
- Labels:
- 9
SpecialProvisionsopen allclose all
Shippingopen allclose all
Remarksopen allclose all
Marine transport (UN RTDG/IMDG)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- Environmentally hazardous substance, solid, n.o.s.
- Chemical name:
- 4,4'-Methylene bis-{2-Chloroaniline}
- Marine pollutant
Remarksopen allclose all
Air transport (UN RTDG/ICAO/IATA)
- UN number:
- 3077
Shipping information
- Proper shipping name and description:
- Environmentally hazardous substance, solid, n.o.s.
- Chemical name:
- 4,4'-Methylene bis-{2-Chloroaniline}
Special provisions / remarks
- Remarks:
- Only regulated by air Into, Out of or Within the United States in containers 10 lbs (4.54 kg) or greater.
SpecialProvisionsopen allclose all
Exposure controls / personal protection
EXPOSURE LIMIT VALUES
Component Country Type Value Remark
4,4'-Methylene-bis(2-chloroaniline) Belgium 8 hours, skin 0,01 ppm
0.01 ppm
Great-Britain TWA, skin 0,005 mg/m3
Switzerland TWA, skin 0,02 ppm
0.02 ppm
Germany AGW 0,02 mg/m3
France VME 0,02 ppm
0.02 ppm
Denmark TWA, skin 0,01 ppm
0.01 ppm
Finland TWA, skin 0,02 ppm
0.02 ppm
STEL, skin 0,06 ppm
0.06 ppm
Spain VLA-ED, skin 0,01 ppm
0.01 ppm
Italy TWA, skin 0,01 ppm
0.01 ppm
the Netherlands MAC-TWA, skin 0,002 ppm
0.002 ppm
Ireland TWA, skin 0,005 mg/m3
NOHSC TWA 0,003 mg/m3
PERSONAL PROTECTION
Respiratory protection:
In the absence of engineering controls sufficient to maintain airborne concentrations below recommended occupational exposure limit values, appropriate respiratory protection should be utilized. The determination of appropriate respiratory protection is best performed, on a case by case basis, taking into consideration the exposure conditions of the particular operation.The respirator manufacturer should be consulted to ensure that the air-purifying cartridges utilized will provide adequate protection for the exposure conditions and period of wear concerned.For emergency conditions where the exposure limit may be greatly exceeded, use an approved positive-pressure self-contained breathing apparatus.
Hand protection / protective gloves:
Chemical resistant protective gloves.
Eye protection:
Full face shield.
Skin protection:
Chemical resistant protective clothing.
Industrial hygiene measures:
Before eating, drinking or smoking, wash hands and face thoroughly with soap and water.
ENGINEERING CONTROLS
Ventilation:
Provide local exhaust or process enclosure ventilation system.
Stability and reactivity
Stability: Stable at ambient temperatures.
Stability - Conditions to avoid:
Excessive temperatures.
Decomposition may occur at temperatures: > 200 °C
Incompatible materials:
Ammonia.
Strong acids.
Finely powdered aluminum and magnesium.
Strong alkalies.
Hazardous combustion products:
Irritating fumes.
Oxides of carbon.
Oxides of nitrogen.
Hydrogen cyanide.
Hydrogen chloride.
o-Chloroaniline upon heating.
Hazardous polymerization: Will not occur.
Disposal considerations
General:
Do not discharge to sewers and natural waters.
Bury in a landfill or incinerate in a furnace in accordance with applicable national and local regulations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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