Registration Dossier
Registration Dossier
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EC number: 202-918-9 | CAS number: 101-14-4
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
- Migrated from Short description of key information:
One LLNA study performed with 4,4-methylenebis(2-chloroaniline) under GLP was available. Also, data from an old in vivo test performed with a substance containing 4,4-methylenebis(2-chloroaniline) and other chloroanilines was available. As the result of the in vivo test was negative, QSAR was applied to support the results of the in vivo test, indicating that none of the individual chloroanilines would cause a positive skin senzitisation reaction.
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
No data available. However, the respiratory system is not considered to be a likely route of exposure.
Justification for classification or non-classification
Based on the above mentioned results, the substance does not need to be classified according to the Dangerous Substance Directive 67/548/EC andCLP Regulation (EC) 1272/2008.
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