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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

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Ecotoxicological information

Toxicity to microorganisms

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Link to relevant study record(s)

Description of key information

Toxicity to microorganisms: 30-min EC50 1000-1800 mg/L (activated sludge)
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate concentrations.

Key value for chemical safety assessment

EC50 for microorganisms:
1 000 mg/L

Additional information

Activated sludge inhibition data (ISO 8192) are available for ethyl methacrylate and indicate a 30-min EC50 of 1000 -1800 mg/L. Further MAA and the lower alkyl methacrylate category members up to the BMA isomers show a low toxicity to micro-organisms while for 2-EHMA no toxicity has been observed up to and above the limit of solubility. See the following table:

Summary of effects on micro-organisms

 

Species

Results

Remarks

Reference

MAA

Pseudomonas putida

16h EC10= 100 mg/l

16 h growth inhibition test, sensitive species

Hanstveit, 1992

MMA

Pseudomonas putida

16h EC3= 100 mg/l

16 h growth inhibition test, sensitive species

Bringmann and Kühn, 1976, 1980ª

MMA

Activated sludge

14 d NOEC = 100 mg/l

Ready biodegradability test, OECD 310 C MITI (I)

CITI, 1992

EMA

Activated sludge

30 min EC50=
1000- 1800 mg/l

ISO8192 (OECD 209) respiration inhibition test

Hund and Fabig, 1989

n-BMA

Pseudomonas putida

18h EC10
253.6 mg/l

18 h growth inhibition test, sensitive species

Fabig and Hund, 1988

i-BMA

Pseudomonas fluorescens

16h EC10> 281 mg/l*

16 h growth inhibition test

Rump(Fresenius), 1988

2-EHMA

Activated sludge

21 d NOEC = 100 mg/l

OECD 301 C

Modified MITI (I) Test

CERI, 1998b

* No growth inhibition with saturated solution