Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-809-9 | CAS number: 110-86-1
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Pyridine has been determined to be readily biodegradable, as shown by the results of the Guideline 301A test conducted by Gerike and Fischer (1979), who reported 91% DOC removal in 19 days, although this test did not specifically show that pyridine biodegradation met the criterion for 70% DOC removal within the 10-day window . In addition, Gerike and Fischer (1979) reported 58% theoretical CO2 evolution and 97% DOC removal in a Guideline 301B test, and reported 97% DOC removal in six days by Guideline 302B. Therefore, pyridine has been determined to be readily biodegradable, but failing the 10-day window.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable but failing 10-day window
Additional information
Pyridine has been shown to be readily biodegradable in the environment, as shown by the results of the Guideline 301A test conducted by Gerike and Fischer (1979); this test showed 91% DOC removal in 19 days, although this test did not specifically show that pyridine biodegradation met the criterion for 70% DOC removal within the 10-day window for ready biodegradability. However, other evidence from Gerike and Fischer (1979) supports extensive biodegradation within the 10-day window, including the reported 58% theoretical CO2 evolution and 97% DOC removal in a Guideline 301B test, and reported 97% DOC removal in six days by Guideline 302B. In a non-guideline study, Stoban et al.(2008) reported 100% biodegradation of 30 mM pyridine and 70mM pyridine in 5 days and 10 days, respectively, by the actinomycete Gordonia terrea. Ruffo et al.(1983) reported 94% biodegradation (CO2evolution) in 8 days by a modified Sturm test. In a non-guideline study, Cassidy et al.(1988) reported 100% biodegradation of 0.2 mg pyridine/L in 4 days and 100% biodegradation of 20 mg pyridine/L in 8 days (by TOC removal). In a non-guideline study, Leeet al.reported 100% biodegradation of 1.88 mM pyridine in 7 days by Pseudonocardia sp. strain M43 (test material analysis). Therefore, although pyridine has been determined to be readily biodegradable but failing the 10-day window, evidence from other tests indicates the likelihood that pyridine may be extensively biodegraded within a period of time less than 10 days.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
