Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Key value for chemical safety assessment

Effects on fertility

Effect on fertility: via oral route
Endpoint conclusion:
no study available (further information necessary)
Effect on fertility: via inhalation route
Endpoint conclusion:
no study available
Effect on fertility: via dermal route
Endpoint conclusion:
no study available
Additional information

A subchronic oral toxicity study was performed with an analogue substance differing in the length of the two alkylchains (C12 versus C18). Details on this valid study (Pharmakon, 1993) are described in the section for repeated dose toxicity. No histopathology findings were observed in organs related to reproductive toxicity up to the highest tested dose of 1000 mg/kg bw.


Short description of key information:
No histopathology effects on reproductive toxicity organs were observed in a valid subchronic oral toxicity study with didodecyl 3,3’-thiodipropionate in rats.

Effects on developmental toxicity

Description of key information

OECD 414, rat: ongoing
OECD 414, rabbit: ongoing

Effect on developmental toxicity: via oral route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via inhalation route
Endpoint conclusion:
no study available
Effect on developmental toxicity: via dermal route
Endpoint conclusion:
no study available

Justification for classification or non-classification

Classification, Labelling, and Packaging Regulation (EC) No. 1272/2008


The available experimental test data are reliable and suitable for classification purposes under Regulation 1272/2008. As a result the substance is not considered to be classified for reproductive toxicity under Regulation (EC) No. 1272/2008.

Additional information