2,3,4-trichlorobut-1-ene

Toxicity to microorganisms

Administrative data

Endpoint:

activated sludge respiration inhibition testing

Type of information:

experimental study

Adequacy of study:

other information

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Guideline study, basic data given

Data source

Reference

Reference 1

Reference Type:

study report

Title:

Unnamed

Year:

1989

Report date:

1989

Reference 2

Reference Type:

secondary source

Title:

2,3,4-TRICHLORO-1-BUTENE

Author:

ECB

Year:

2000

Bibliographic source:

ECB IUCLID dataset

Reference 3

Reference Type:

secondary source

Title:

2,3,4-TRICHLORO-1-BUTENE - CAS No: 2431-50-7

Author:

OECD

Year:

1993

Bibliographic source:

Screening Information Data Set (SIDS) of OECD High Production Volume Chemicals Programme, (1993)

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

2,3,4-trichlorobut-1-ene

EC Number:

219-397-9

EC Name:

2,3,4-trichlorobut-1-ene

Cas Number:

2431-50-7

Molecular formula:

C4H5Cl3

IUPAC Name:

2,3,4-trichlorobut-1-ene

Sampling and analysis

Analytical monitoring:

no

Test solutions

Vehicle:

no

Details on test solutions:

directly weighted into the test vessels

Test organisms

Test organisms (species):

activated sludge

Details on inoculum:

- Laboratory culture: yes, laboratory treatment plant

Study design

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

3 h

Test conditions

Nominal and measured concentrations:

Nominal concentrations: 100, 180, 320, 560, 1000, 10000 mg/L

Details on test conditions:

TEST MEDIUM / WATER PARAMETERS
- Source/preparation of medium: according to guideline (nutrient medium: ISO 8192-1986)

Reference substance (positive control):

yes

Remarks:

3,5-dichlorphenol

Results and discussion

Effect concentrations

Effect concentrations 1

Duration:

3 h

Dose descriptor:

EC10

Effect conc.:

59.7 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

inhibition of total respiration

Remarks:

respiration rate

Effect concentrations 2

Duration:

3 h

Dose descriptor:

EC50

Effect conc.:

394 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

inhibition of total respiration

Remarks:

respiration rate

Effect concentrations 3

Duration:

3 h

Dose descriptor:

other: EC5

Effect conc.:

35 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

inhibition of total respiration

Remarks:

respiration rate