Registration Dossier
Registration Dossier
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EC number: 295-458-3 | CAS number: 92045-76-6 A complex combination of hydrocarbons obtained from residual oils by solvent crystallisation and treated with hydrogen in the presence of a catalyst. It consists predominantly of saturated straight and branched chain hydrocarbons having carbon numbers predominantly greater than C25.
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
Read across justification
Several criteria justify the use of the read across approach to fill data gaps for paraffin and hydrocarbon waxes using other lubricant base oil analogs. Primarily the basis for the read-across is the similar physical chemical properties shared by the paraffin and hydrocarbon waxes and other lubricant base oils.
In a read-across key static 96-hour short-term fathead minnow (Pimephales promelas) limit test (OECD 203; KS=1), 10 animals/loading were exposed to the Water Accommodated Fraction (WAF) of an other lubricant base oil, Basestock Solvent Neutral 600 (MRD-94 -981) at a nominal concentration of 100 mg/L. The LL50 was > 100 mg/L and the NOEL was ≥100 mg/L (Exxon, 1995b).
This study is scientifically sound and satisfies the guideline requirement for short-term toxicity to fish.
Supporting data estimated from the PETROTOX computer model show no acute toxicity of paraffin and hydrocarbon wax to freshwater fish at or below its maximum attainable water solubility (Redman et al., 2010b). These data support the applied read across.
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