Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

No reliable data are available for the hydrolysis of isononyl phosphate. However, reliable data are available for the analogue,Phosphoric acid, 2-ethylhexyl ester (CAS 12645 -31 -7) and are included in the dossier.

One key study, Butler & White (2011) is presented assessing the hydrolysis of the substance, conducted in accordance with OECD Guideline 111 - "Hydrolysis as a Function of pH". The study indicates that the test item is stable in aqueous solution at pH 4, 7 and 9, each with a half-life >1 year.

Reliable data are available for the biodegradation of isononyl phosphate in water screening tests and is included in the dossier. Additionally, reliable data are available for the analogue,Phosphoric acid, 2-ethylhexyl ester (CAS 1645 -31 -7) and are included in the dossier.

Brunswik-Titze, Gartiser & Jäger (2003) conducted a reliable biodegradation study for isononyl phosphate following OECD 301B guidelines and was GLP compliant. Study result indicate the test substance can be considered readily biodegradable, failing the 10 -day window. Additional biodegradation studies with the analogue,Phosphoric acid, 2-ethylhexyl ester, provide supporting evidence that the substance is readily biodegradable.

In accordance with column 2 of REACH Annex IX (9.3.2) a bioaccumulation study in aquatic species (preferably fish) does not need to be conducted if: - the substance has a low potential for bioaccumulation (for instance a log kow ≤3) and/or a low potential to cross biological membranes. The substance has a low octanol/water partition coefficient value range with an average log Pow = 1.86. The substance is therefore not considered to have the potential to accumulate in organisms and a bioaccumulation study is not required.

No reliable data are available for the adsorption of isononyl phosphate. However, reliable data are available for the analogue,Phosphoric acid, 2-ethylhexyl ester (CAS 12645 -31 -7) and are included in the dossier.

In a single key study by Butler and While (2011), the adsorption coefficient was determined in accordance with OECD Guideline 121 (HPLC Estimation Method). The adsorption coefficient (Koc) ofPhosphoric acid, 2-ethylhexyl esterhas been determined to be less than 17.8 (log10Koc <1.25).