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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

48h EL50 = >100 mg/L (Daphnia magna); Goodband & Mullee (2011); OECD 202
48h LL50 = 117.4 mg/L (Acartia tonsa); Furst (2002); ISO/CD 14669
48h LL50 = 1410 mg/L (Acartia tonsa); Torp (1996); ISO TC147/SC5/WG2

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
100 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
117.4 mg/L

Additional information

No reliable data are available for the short-term aquatic toxicity of isononyl phosphate to aquatic invertebrates. However, reliable data are available for the analogue,Phosphoric acid, 2-ethylhexyl ester (CAS 12645 -31 -7) and are included in the dossier.

Three key studies are submitted for the short-term toxicity to aquatic invertebrates endpoint, one for a freshwater species and two for marine species. Each study was conducted using a standard approach for testing poorly soluble, multi-component substances, the preparation of a water accommodated fraction (WAF). As such, the effect values are presented as loading rates (e.g. LL50or EL50), and not measured aqueous concentrations. Goodband & Mullee (2011) provided a 48h EL50 = >100 mg/L for Daphnia magna. Furst (2002) provided a 48hr LL50 of 117.4 mg/L for the marine invertebrate, Acartia tonsa.