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Particle size distribution (Granulometry)

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Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
21 May 2013
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
Not performed under GLP
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
GLP compliance:
no
Type of method:
determination of fibre length and diameter distributions
Type of distribution:
volumetric distribution
Key result
Percentile:
D50
Mean:
ca. 35.7 µm
St. dev.:
0.724
Remarks on result:
other: Mean of 3 determinations
Percentile:
D10
Mean:
6.9 µm
St. dev.:
0.135
Percentile:
D50
Mean:
35.7 µm
St. dev.:
0.724
Percentile:
D90
Mean:
163.234 µm
St. dev.:
5.934
No.:
#1
Size:
0.417 µm
Distribution:
100 %
No.:
#2
Size:
6.607 µm
Distribution:
90.92 %
No.:
#3
Size:
11.482 µm
Distribution:
80.83 %
No.:
#4
Size:
17.378 µm
Distribution:
70.57 %
No.:
#5
Size:
22.909 µm
Distribution:
62.85 %
No.:
#6
Size:
34.674 µm
Distribution:
50.62 %
No.:
#7
Size:
45.709 µm
Distribution:
42.42 %
No.:
#8
Size:
69.183 µm
Distribution:
30.67 %
No.:
#9
Size:
120.226 µm
Distribution:
16.66 %
No.:
#10
Size:
316.228 µm
Distribution:
0 %
Conclusions:
The mass median diameter of Promaxon T was found to be 35.700 µm. No particles were found under 0.417 µm and above 316.228 µm under the conditions of this test.
Executive summary:

The granulometry of Promaxon T was determined with a Mastersizer 2000. The mass median diameter was found to be 35.700 µm. No particles were found under 0.417 µm and above 316.228 µ under the conditions of this test.

Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
05-08-2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
Not performed under GLP
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
GLP compliance:
no
Type of method:
determination of fibre length and diameter distributions
Type of distribution:
volumetric distribution
Key result
Percentile:
D50
Mean:
61.253 µm
St. dev.:
0
Remarks on result:
other: no st dev due to single determination
Percentile:
D10
Mean:
13.869 µm
St. dev.:
0
Percentile:
D50
Mean:
61.253 µm
St. dev.:
0
Percentile:
D90
Mean:
116.086 µm
St. dev.:
0
No.:
#1
Size:
1.445 µm
Distribution:
100 %
No.:
#2
Size:
13.183 µm
Distribution:
90.49 %
No.:
#3
Size:
30.2 µm
Distribution:
82.08 %
No.:
#4
Size:
45.709 µm
Distribution:
67.96 %
No.:
#5
Size:
60.256 µm
Distribution:
51.13 %
No.:
#6
Size:
69.183 µm
Distribution:
41.4 %
No.:
#7
Size:
79.433 µm
Distribution:
31.65 %
No.:
#8
Size:
91.201 µm
Distribution:
22.6 %
No.:
#9
Size:
138.038 µm
Distribution:
4.09 %
No.:
#10
Size:
181.97 µm
Distribution:
0 %
Conclusions:
The mass median diameter was found to be 61.253 µm. No particles were found under 1.445 µm and above 181.970 µm under the conditions of this test.
Executive summary:

The granulometry of Promaxon was determined with a Mastersizer 2000. The mass median diameter was found to be 61.253 µm. No particles were found under 1.445 µm and above 181.970 µm under the conditions of this test.

Description of key information

The mass median diameter: Promaxon T, 35.700µm. Promaxon: 61.253 µm.  

Additional information

The granulometry of crystalline calcium silicate hydrates (xonotlite - tobermorite) was investigated according to OECD guideline 110 under GLP using the sedimentation method. This test was disregarded.

The granulometry of Promaxon T was determined with a Mastersizer 2000. The mass median diameter was found to be 35.700 µm. No particles were found under 0.417 µm and above 316.228 µ under the conditions of this test.

The granulometry of Promaxon was determined with a Mastersizer 2000. The mass median diameter was found to be 61.253 µm. No particles were found under 1.445 µm and above 181.970 µm under the conditions of this test.