Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 221-641-4 | CAS number: 3173-72-6
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: documentation insufficient for assessment
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 974
- Report date:
- 1974
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- no data
- GLP compliance:
- no
Test material
- Reference substance name:
- 1,5-naphthylene diisocyanate
- EC Number:
- 221-641-4
- EC Name:
- 1,5-naphthylene diisocyanate
- Cas Number:
- 3173-72-6
- Molecular formula:
- C12H6N2O2
- IUPAC Name:
- 1,5-diisocyanatonaphthalene
- Reference substance name:
- Desmodur 15
- IUPAC Name:
- Desmodur 15
- Details on test material:
- - Name of test material (as cited in study report): 1,5-Naphthylendiisocyanat (Desmodur 15)
- Physical state: solid
- Purity: 99.8 %
Constituent 1
Constituent 2
Test animals
- Species:
- rat
- Strain:
- Wistar
- Sex:
- female
- Details on test animals or test system and environmental conditions:
- TEST ANIMALS:
- Source: Winkelmann (Borchen, Germany)
- Weight at study initiation: 120-140 g
Administration / exposure
- Route of administration:
- subcutaneous
- Vehicle:
- water
- Details on exposure:
- no data
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
- Details on study design:
- no data
- Statistics:
- no data
Results and discussion
Effect levels
- Sex:
- female
- Dose descriptor:
- LD50
- Effect level:
- > 5 000 mg/kg bw
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
