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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

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Administrative data

Link to relevant study record(s)

Description of key information

Based on the calculated log Kow of 4.37, a BCF of about 354 for 1,5 -naphthalene diisocyanate is estimated using the EPI Suite program, v. 4.0. (Currenta, 2010). As 1,5 -naphthalene diisocyanate hydrolysis with a half-life time of less than 1 hour in aquatic media, the estimated BCF is only of theoretical interest. The bioconcentartion factor (BCF) of the hydrolysis product 1,5-naphthylene diamine in carp (Cyprinus carpio) was determined by the Chemicals Inspection & Testing Institute of Japan (MITI, 1992). The test was conducted in accordance with "Bioaccumulation test of chemical substance in fish and shellfish", which corresponds to the OECD TG 305C, "Bioaccumulation: Degree of bioconcentration in fish", 1981. The fish were exposed to concentrations of 0.2 mg/l and 0.002 mg/l. A BCF  of < 4.5 at the low concentration and a BCF <0.4 - 1.5 at the higher concentration were obtained.

Key value for chemical safety assessment

BCF (aquatic species):
4.5 dimensionless

Additional information

The key value should read < 4.5.