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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Diss Factsheets

Ecotoxicological information

Toxicity to microorganisms

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Description of key information

NOEC(3h) >= 1000 mg/L, EC50(3h) > 1000 mg/L

Key value for chemical safety assessment

Additional information

The inhibition of the respiration rate of activated sludge exposed to Aluminium silicate and titanium oxide matrix doted with vanadium, nickel, and antimony was determined according to OECD 209 under GLP (Muckle 2010, RL1). Up to the highest tested concentration of 1000 mg/l (nominal) no inhibition was observed and an EC50(3h) > 1000 mg/L and a NOEC(3h) >= 1000 mg/L was stated.

Additional data for toxicity to microorganisms are available for the following source substances which serve as potential data sources for the analogue approach of Aluminium silicate and titanium oxide matrix doted with vanadium, nickel, and antimony:

- Source chemical 1 - Fluidized catalytic cracking (FCC) catalysts:

EC50(16h) = 1400 mg/L, EC10(16h) = 2800 mg/L, inhibition of growth rate with P.putida, Weyandt 1998

- Source chemical 2 - Zeolite, cuboidal, crystalline, synthetic, non-fibrous:

EC50(16h) = 950 mg/L, EC10(16h) = 330 mg/L, inhibition of growth rate with P.putida, Hanstveit and Pullens 1992

In accordance with the target substance, the available data for the source substances also provide a low potential for toxicity to microorganisms.

The respective references for the source substance data can be found in the data matrix of the justification for the analogue approach, which can be found either in the CSR or as attachment in Iuclid section 13.