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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
14 February - 24 June 2003
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Guideline:
other: according to TNO-PML Standard Operation Procedure Q 222-W-014, 'Working with the Malvern Particle Size Analyser', Version 3
Deviations:
no
Qualifier:
equivalent or similar to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Version / remarks:
November 1999
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
Laser scattering/diffraction
Type of distribution:
volumetric distribution
Key result
Mean:
< 1.2 µm
Remarks on result:
other: The particle size distribution of the test substance is largely < 1.2 μm.
Conclusions:
The test substance consists largely of agglomerates. Sonication was applied to disperse the agglomerates. This resulted in primary particles which were largely smaller than 1.2 µm, the detection limit of the analyser used. 

Description of key information

The particle size distribution of the test substance is largely < 1.2 μm (laser diffraction method).

Additional information