Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 274-126-1 | CAS number: 69808-32-8
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 23 SEPTEMBER 2019 to 16 JANUARY 2020
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
- Report date:
- 2020
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Version / remarks:
- OECD Guidelines for the Testing of Chemicals, Method No. 105, adopted 27Jul. 1995: "Water Solubility".
Comission Regulation (EU) No 260/2014 amending Regulation (CE) No 440/2008: Method A.6: "Water solubility", adopted 24 January 2014. - Deviations:
- yes
- Remarks:
- These deviations were assessed by the study director on Jan. 17th, 2020
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- column elution method
Test material
- Reference substance name:
- 1-butyl-5-[(4-chlorophenyl)azo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxonicotinonitrile
- EC Number:
- 274-126-1
- EC Name:
- 1-butyl-5-[(4-chlorophenyl)azo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxonicotinonitrile
- Cas Number:
- 69808-32-8
- Molecular formula:
- C17H17ClN4O2
- IUPAC Name:
- 1-butyl-5-[(4-chlorophenyl)azo]-1,2-dihydro-6-hydroxy-4-methyl-2-oxonicotinonitrile
- Test material form:
- solid: particulate/powder
- Details on test material:
- - State of aggregation: powder
- Particle size distribution: not determined
- Mass median aerodynamic diameter (MMAD): not determined
- Geometric standard deviation (GSD): not determined
- Shape of particles: not determined
- Surface area of particles: not determined
- Crystal structure: not determined
- Coating: none
- Surface properties: not determined
- Density: 1.3526 ± 0.0010 g/cm3 at 20.0 ± 0.2°C
- Moisture content: <0.5%
- Residual solvent: not detected
- Activation: none
- Stabilisation: none
- Other:
Constituent 1
Results and discussion
Water solubility
- Key result
- Water solubility:
- >= 5.74 - <= 6.98 µg/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 1 g/L
- Incubation duration:
- ca. 1 h
- Temp.:
- 20 °C
- pH:
- ca. 6
- Remarks on result:
- other: Demineralided water was used.
- Details on results:
- All samples showed good correspondence. Standard deviation within the samples as well as all over the plateau was very low. The difference of concentrations measured for both flow rates was determined as 11.27%, thus was below 30%, therefore independency of solubility and flow rate is given.
no observations arousing doubts concerning the accuracy of the results and the validity of the study were made.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
