Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 309-363-2 | CAS number: 100231-63-8
Endpoint summary
Administrative data
Description of key information
Additional information
Only limited data is available for the aquatic toxicity of the target substance D-Glucopyranose, oligomeric, pentyl glycosides (CAS 100231-63-8). Therefore, read-across was performed to the two structurally and chemically closely related source substances D-Glucopyranose, oligomeric, butyl glycoside (CAS 31387-97-0) and D-Glucopyranose, oligomers, hexyl glycosides (CAS 54549-24-5) in accordance with Regulation (EC) No 1907/2006 Annex XI, 1.5 in order to meet the standard information requirements laid down in Annex VII of REACh Regulation (EC) No 1907/2006.
The target and source substances only differ in the carbon chain length of the glycosyl group, which is C5 in the target substance and C4 and C6 in the source substances CAS 31387-97-0 and CAS 54549-24-5, respectively. Based on this high degree of physico-chemical similarity, the target substance is expected to exhibit a similar ecotoxicological profile as the selected source substances. Therefore, the source substances are considered suitable representatives for the prediction of the aquatic toxicity of the target substance by interpolation from source substance data in accordance with Annex XI, Item 1.5, of Regulation (EC) No 1907/2006. A detailed read-across approach justification is provided in IUCLID section 13.
By means of the read-across approach, GLP-guideline studies for the freshwater and marine compartments are available for the short-term toxicity of the target substance to aquatic invertebrates as well as for the toxicity to aquatic algae.
For the short-term toxicity to aquatic invertebrates, two key studies and two supporting studies are available. The key studies were conducted according to OECD guideline 202 with the source substances CAS 31387-97-0 and CAS 54549-24-5. The supporting studies were conducted according to OECD guideline 202 for freshwater and ISO 14669-1999 for marine water with the source substance CAS 54549-24-5. In all tests, no hazard to aquatic invertebrates was recorded in freshwater and marine water.
For the toxicity to aquatic algae, two key studies and one supporting study are available. The key studies were conducted according to OECD guideline 201 for freshwater and ISO 10253 for marine water with source substances CAS 31387-97-0 and CAS 54549-24-5, respectively. The supporting study was conducted according to OECD guideline 201 with source substance CAS 54549-24-5. In all tests, no hazard to aquatic algae was recorded.
The toxicity control of the available ready biodegradation study showed that the test item did not inhibit activated sludge microorganisms. The toxicity control reached 91% biodegradation after 14 d, resulting in a NOEC (14 d) of ≥ 27.1 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
