Reaction mass of N-butylphthalimide and N-sec-butylphthalimide and N-propylphthalimide

Acute Toxicity: dermal

Administrative data

Endpoint:

acute toxicity: dermal

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018 - study in progress

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

OECD Guideline 402 (Acute Dermal Toxicity)

GLP compliance:

yes (incl. QA statement)

Test material

Test material information

Constituent 1

Reference substance name:

N-propylphthalimide

EC Number:

226-189-1

EC Name:

N-propylphthalimide

Cas Number:

5323-50-2

Molecular formula:

C11H11NO2

IUPAC Name:

2-propyl-1H-isoindole-1,3(2H)-dione

Constituent 2

Reference substance name:

N-sec-butylphthalimide

EC Number:

233-295-1

EC Name:

N-sec-butylphthalimide

Cas Number:

10108-61-9

Molecular formula:

C12H13NO2

IUPAC Name:

2-sec-butyl-1H-isoindole-1,3(2H)-dione

Constituent 3

Reference substance name:

N-butylphthalimide

EC Number:

216-157-5

EC Name:

N-butylphthalimide

Cas Number:

1515-72-6

Molecular formula:

C12H13NO2

IUPAC Name:

2-butyl-1H-isoindole-1,3(2H)-dione

impurity 1

Reference substance name:

Unknown impurities.

Molecular formula:

Not available as unknown impurities.

IUPAC Name:

Unknown impurities.

1

Reference substance name:

Water

EC Number:

231-791-2

EC Name:

Water

Cas Number:

7732-18-5

Molecular formula:

H2O

IUPAC Name:

water

Test material form:

liquid

Details on test material:

Batch CNAA053604
Color: clear yellowish
Form: liquid
Storage conditions: Room temperature in a closed container, protected from light.

Results and discussion

Effect levels

Key result

Dose descriptor:

LD50

Effect level:

> 0 mg/kg bw

Remarks on result:

other: preliminary results, study in progress (05/2018)