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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2018 - study in progress
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 402 (Acute Dermal Toxicity)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
N-propylphthalimide
EC Number:
226-189-1
EC Name:
N-propylphthalimide
Cas Number:
5323-50-2
Molecular formula:
C11H11NO2
IUPAC Name:
2-propyl-1H-isoindole-1,3(2H)-dione
Constituent 2
Chemical structure
Reference substance name:
N-sec-butylphthalimide
EC Number:
233-295-1
EC Name:
N-sec-butylphthalimide
Cas Number:
10108-61-9
Molecular formula:
C12H13NO2
IUPAC Name:
2-sec-butyl-1H-isoindole-1,3(2H)-dione
Constituent 3
Chemical structure
Reference substance name:
N-butylphthalimide
EC Number:
216-157-5
EC Name:
N-butylphthalimide
Cas Number:
1515-72-6
Molecular formula:
C12H13NO2
IUPAC Name:
2-butyl-1H-isoindole-1,3(2H)-dione
impurity 1
Reference substance name:
Unknown impurities.
Molecular formula:
Not available as unknown impurities.
IUPAC Name:
Unknown impurities.
1
Chemical structure
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
water
Test material form:
liquid
Details on test material:
Batch CNAA053604
Color: clear yellowish
Form: liquid
Storage conditions: Room temperature in a closed container, protected from light.

Results and discussion

Effect levels
Key result
Dose descriptor:
LD50
Effect level:
> 0 mg/kg bw
Remarks on result:
other: preliminary results, study in progress (05/2018)

Applicant's summary and conclusion

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