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EC number: 255-002-6
CAS number: 40615-36-9
The toxicity of 4,4'-Dimethoxytrityl
chloride was tested according to OECD guidelines 201 and 202 for acute
toxicity studies with aquatic invertebrates (Daphnia magna) and
algae (Pseudokirchneriella subcapitata). No toxic effect on D. magna
was observed up to the limit of water solubility (NOEC ≥ 100 mg/L
nominal, corresponding to 4.3 mg/L measured). For P. subcapitata a
72 h ErC50 of 1.629 mg/L (95 % C.L. 1.079 – 2.417 mg/L) was determined.
The 72 h NOErC is 0.537 mg/L.
Toxicity to invertebrates:
Daphnia magna Straus was exposed for
48 hours to 4,4'-Dimethoxytrityl chloride in a static short-term
toxicity study according to the OECD guideline 202 (2004) and in
compliance with the OECD-GLP principles. The study was conducted as
limit test with a measured concentration of 4.3 mg/L (limit of water
solubility; nominal concentration of 100 mg/L). The test concentrations
were determined analytically by HPLC-UV. As the measured test item
concentrations are not within ± 20 % of the nominal loading rate,
according to OECD 202 (2004) and OECD 23 (2000), all results are given
in relation to the analytically measured test item concentrations.
No effect on D. magna was observed.
Toxicity to algae:
The freshwater algae
Pseudokirchneriella subcapitata was exposed to 4,4'-Dimethoxytrityl
chloride for 72 hours in a static toxicity study according to the OECD
guideline 201 (2006) and in compliance with the OECD-GLP principles. In
this study a 72 h ErC50 (endpoint: growth rate) of 1.629 mg/L (95 % C.L.
1.079 - 2.417 mg/L) and a 72 h NOErC (endpoint: growth rate) of 0.947
mg/L were determined. The test concentrations were determined
analytically by HPLC-UV.
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