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EC number: 251-459-0
CAS number: 33329-35-0
Both nominal and actual exposure concentrations were determined for the
LC50 study. Nominal concentrations were determined by weighing the
amount of test material placed in the generator reservoir prior to
exposure and then again following exposure. The difference in weight
was divided by the total air passed through the chamber during the
exposure period. Actual exposure concentrations were determined by
standard gravimetric techniques.
The results indicated that nominal concentrations were higher than
actual concentrations, e.g. 11.3 mg/L versus 2.8 mg/L for the highest
concentration. Since B.P.>200°C, and vapour pressure=0.172
lb/inch3) this is a liquid material with low volatility, the actual
measured concentrations seem more appropriate for evaluation of toxicity.
In conclusion, at actual exposure concentrations of 1.1-2.8 mg/L
(nominal concentrations of 3.6-11.3 mg/L) for four hours produced signs
of toxicity and deaths in rats. The combined male and female 4-hour LC50
values for actual measured concentrations and nominal concentrations
were estimated to be 1.9 mg/L and 6.9 mg/L, respectively.
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