Fatty acids, C8-10, C12-18-alkyl esters

Sensitisation data (human)

Administrative data

Endpoint:

sensitisation data (humans)

Type of information:

experimental study

Adequacy of study:

disregarded due to major methodological deficiencies

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

other: Only short abstract available. The analytical purity of the test substance was not specified, the available documentation is limited, the test substance concentration is not specified.

Data source

Reference

Reference Type:

other company data

Title:

Unnamed

Year:

1968

Report date:

1968

Materials and methods

Principles of method if other than guideline:

20 volunteers were exposed to the test substance in a sensitisation study, using a modified version of the test described by Schneider (Tübingen, Germany). The induction was performed by applying the test substance daily for 14 consecutive days. The challenge was performed folllowing a 14-day recovery period.

GLP compliance:

no

Test material

Test material information

Constituent 1

Reference substance name:

Fatty acids, C8-10, C12-18-alkyl esters

EC Number:

306-082-7

EC Name:

Fatty acids, C8-10, C12-18-alkyl esters

Cas Number:

95912-86-0

Molecular formula:

Unspecified

IUPAC Name:

Fatty acids, C8-10, C12-18 (even numbered)-alkyl esters

Details on test material:

- Name of test material (as cited in study report): only trade name given
- Analytical purity: no data

Method

Type of population:

general

Ethical approval:

not specified

Subjects:

- Number of subjects exposed: 20

Controls:

No data

Route of administration:

dermal

Details on study design:

TYPE OF TEST(S) USED: patch test (epicutaneous test)

ADMINISTRATION
- Other: the induction was performed by applying the test substance daily for 14 consecutive days. The challenge was performed 14 days later.

Results and discussion

Results of examinations:

OTHER RESULTS:
No sensitizing effect was observed following the challenge exposure.