Registration Dossier
Registration Dossier
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Diss Factsheets
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EC number: 205-250-6 | CAS number: 136-52-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Relevant and reliable data that could be used for classification for short-term toxicity for freshwater fish were retrieved for 3 different species. The LC50s ranged from 0.8 mg Co/L for Oncorhynchus mykiss to 85 mg Co/L for Danio rerio. Test results were obtained in experiments that followed international accepted guidance and were based on measured levels of dissolved cobalt as cobalt dichloride. No relevant and reliable data that could be used for classification for short-term toxicity for marine fish were identified. Thus, no LC50 values were derived for short-term toxicity for marine fish.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.8 mg/L
Additional information
Ten high quality studies were included in the acute toxicity to aquatic fish database for freshwater fish. Three different species were represented in the studies, and distributed between the Danio rerio, Oncorhynchus mykiss and Pimephales promelas species. Median lethal concentration (LC50) values ranged from 0.8 mg Co/L (Oncorhynchus mykiss, Pacific EcoRisk, 2005) to 85 mg Co/L (Danio rerio, CDI, 2008b).
Marine:
Only one study was identified which examined the acute toxicity of cobalt to marine fish species, Fundulus heteroclitus.
The study was designated as category RL3 because the level of study documentation was incomplete and the reported values were based on the nominal (i.e., unmeasured) cobalt concentrations. Thus, no acute aquatic fish tests were judged sufficient to carry forward in subsequent risk evaluations.
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