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EC number: 239-594-3
CAS number: 15546-11-9
A read across approach has been taken to fulfil this endpoint using a structurally similar substance as there is no availbale data for this substance.The following key study was provided to fulfil the data requirement: Hanstveit Ir. R. (2003) 1,3,2-Dioxastannepin-4,7-dione, 2,2-dibutyl- (CAS # 78-04-6, Dibutyltin maleate, DBTM): Determination of the ready biodegradability in a Manometric Respiration Test. Testing laboratory: TNO, Project Organisation, Ecotoxicology, Utrechtseweg 48, P.O. Box 360, 3700 AJ Zeist, The Netherlands. Owner company: Organotin Environmental Programme (ORTEP) Association, Stabilizer Task Force. Report No.: V4017/01. Report date: 2003-09-24The biodegradation of dibutyltin maleate was determined in a study performed in compliance with GLP and to the methods OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test) and EU Method C.4-D (Determination of the "Ready" Biodegradability - Manometric Respirometry Test). The study was considered reliable and adequate for assessment and accordingly assigned a reliability score of 2. The percentage degradation of 1,3,2-dioxastannepin-4,7-dione, 2,2-dibutyl- after 28 days of incubation was approximately 3% in a manometric respiration test at a test substance concentration of 37.7 mg.l-1, calculated from the Theoretical Oxygen Demand (ThODNH3) (1.38 mg O2.mg-1) of test substance. The biodegradation of 1,3,2-dioxastannepin-4,7-dione, 2,2-dibutyl- did not exceed the pass level of 60% ThODNH3 within 28 days and, therefore, is classified as not readily biodegradable.
The key study Hanstveit Ir. R. (2003), was performed in compliance with
GLP and to the guidelines OECD 301 F and EU Method C.4-D. The study was
considered highly reliable and adequate for assessment and therefore
assigned a reliabiltiy score of 2, due to it being read-across data.
Under the conditions of the test dibutyltin maleate was found to not be
Read-across between dibutyltin compounds to dibutyltin methylmaleate
concerning aquatic toxicity endpoints was considered appropriate as
dibutyltin and octyltins are known to hydrolyse rapidly in water (as
presented by Yoder 2003, under the data requirement hydrolysis), and
form, in the case of dibutyltins, dibutyltin oxide.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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