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EC number: 239-594-3
CAS number: 15546-11-9
In an acute oral toxicity study equivalent to OECD Guideline No. 401,
groups of 10 young adult Sprague-Dawley rats/sex were given a single
oral dose of the test item Prosper MSL (96 %
in vegetable oil at doses of 0 (vehicle control), 100, 200, 400, 800,
and 1600 mg/kg bw and observed for 14 days.
Oral LD50 Females: 419 mg/kg bw (95% C.L. 229.78 to 764.46 mg/kg bw)
Oral LD50 Males: 526 mg/kg bw (95% C.L. 319.59 to 866.74 mg/kg bw)
Treatment related clinical signs were lethargy, motor incoordination,
altered faeces consistency, nosebleeding and body weight retardation.
There were no treatment related necropsy findings in animals found dead
within the observation period or sacrificed at study termination.
is of moderate toxicity based on the oral LD50 of 526 and 419 mg/kg bw
in male and female rats, respectively.
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