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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Range finding toxicty data:List VIII
Author:
Carpenter et al
Year:
1974
Bibliographic source:
Toxicology and Applied Pharmacology. 28 (1974), 313
Reference Type:
review article or handbook
Title:
RTECS Number : GB7575000
Author:
TXAPA9 Toxicology and Applied Pharmacology.
Year:
2012
Bibliographic source:
RTECS (Registry of Toxic Effects of Chemical Substances); (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 28,313,1974

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Range finding toxicity study
GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Reference substance name:
Chromium(III) 4-oxopent-2-ene-2-olate
EC Number:
244-526-0
EC Name:
Chromium(III) 4-oxopent-2-ene-2-olate
Cas Number:
21679-31-2
IUPAC Name:
chromium(3+) tris(2,4-dioxopentan-1-olate)

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
6 350 other: mg/kg
Based on:
test mat.
Remarks on result:
other: other details not known

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Acute dermal toxicity value of chromium(III) 4-oxopent-2-ene-2-olate to rabbit is found to be LD50: 6350 mg/kg
Executive summary:

Acute dermal toxicity value of chromium(III) 4-oxopent-2-ene-2-olate to rabbit is found to be LD50: 6350 mg/kg. This end point result indicate that the substance will be non toxic to dermal category.