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EC number: 248-654-8
CAS number: 27776-01-8
For category rationale and justification see attached category
documentation under section 13 "Assessment Reports".
A study was performed to assess the acute dermal toxicity of the test
material in the Sprague-Dawley strain rat. The method used followed that
described in the OECD Guidelines for Testing of Chemicals (1981) No. 402
"Acute Dermal Toxicity" referenced as Method B3 in Annex V of EEC
Commission Directive 84/449/EEC.
A group of ten animals (five males and five females), was given a
single, 24-hour, semi-occluded dermal application of the test material
to intact skin, at a dose level of 2000 mg/kg bodyweight.
There were no deaths. No evidence of systemic toxicity or skin
irritation were noted during the study.
All animals showed expected gain in bodyweight during the study period.
No abnormalities were noted at necropsy of animals killed at the end of
The acute dermal median lethal dose (LD50) of the test material in the
Sprague-Dawley strain rat was found to be greater than 2000 mg/kg body-
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