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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP. Guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report date:
2011

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Qualifier:
according to guideline
Guideline:
EU Method C.1 (Acute Toxicity for Fish)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Ethyl [(4-methylphenyl)sulphonyl]carbamate
EC Number:
226-952-9
EC Name:
Ethyl [(4-methylphenyl)sulphonyl]carbamate
Cas Number:
5577-13-9
Molecular formula:
C10H13NO4S
IUPAC Name:
ethyl [(4-methylphenyl)sulfonyl]carbamate

Sampling and analysis

Analytical monitoring:
not specified

Test organisms

Test organisms (species):
Cyprinus carpio

Study design

Test type:
static
Limit test:
yes
Total exposure duration:
96 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
24 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Basis for effect:
mortality (fish)
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Basis for effect:
mortality (fish)
Duration:
72 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Basis for effect:
mortality (fish)
Duration:
96 h
Dose descriptor:
NOEC
Effect conc.:
100 mg/L

Any other information on results incl. tables

Sublethal observations / clinical signs:

No mortality or clinical effects were observed.

Applicant's summary and conclusion

Conclusions:
Under the conditions of the test Tolfamato induce no visible or lethal effects in carp at or below an analytically confirmed nominal concentration of 100 mg/l (NOEC).
The 96h-LC50 exceeded 100 mg(l based on analytically confirmed nominal concentrations.

The 96h-LC50 exceeded 100 mg/l based on analytically confirmed nominal concentrations