Registration Dossier
Registration Dossier
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EC number: 208-778-5 | CAS number: 541-41-3
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
EtCF was tested for mutagenicity with and without metabolic activation in S. typhimurium TA98, TA100, TA1535 and TA1537 at dose levels of 5 -5000 µl/plate. The test followed OECD Guideline 471. No increase in the number of revertants was detected in any strain with and without metabolic activation. Vehicle controls and positive controls were valid. Cytotoxicity was found depending on the strain and metabolic activation. No precipitation was reported (BASF AG, 1988d).
Short description of key information:
Ethyl chlorformate is non mutagenic in the Ames test.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
No classification concerning mutagenic properties is warranted as classification criteria according EU Regulation 67/548 and Eu Rgulation 1272/2008 are not met.
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