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REACH

Ethyl chloroformate

EC number: 208-778-5 | CAS number: 541-41-3

Life Cycle description
Uses advised against

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

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Administrative data

Link to relevant study record(s)

Description of key information

Hydrolysis product ethanol: With high probability acutely not harmful to aquatic invertebrates.
Hydrolysis product HCl: Acutely very toxic for aquatic invertebrates (pH dependent).

Key value for chemical safety assessment

Additional information

There are no data available regarding the toxic effect of the parent compound to aquatic invertebrates. The hydrolysis product ethanol was tested in a acute toxicity test with Ceriodaphnia dubia following ASTM Standard E729 -80. The resulting EC₅₀ (48 h) was 5012 mg/L, indicating no harmful effects (OECD, 2005).

The hydrolysis product HCl showed acutely very toxic effects due to low pH: EC₅₀ (48 h) = 0.492 mg/L (OECD, 2002).

Species

Results

Remarks

Reference

Ceriodaphnia dubia

EC₅₀ (48 h) = 5012 mg/L (nominal); ASTM Standard E729-80

Hydrolysis product ethanol; reliability: 2, key study

OECD, 2005

Daphnia magna

EC₅₀ (48 h) = 0.492 mg/L (acid equivalent to pH 5.3), semi-static, with analytical monitoring, OECD TG 202

Hydrolysis product HCl; reliability: 2

OECD, 2002

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