Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-158-8 | CAS number: 1308-14-1
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Information from a peer reviewed Assessment Report, original study not available.
Data source
Reference
- Reference Type:
- other: Peer reviewed assessment report
- Title:
- Unnamed
- Year:
- 2 009
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 405 (Acute Eye Irritation / Corrosion)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Chromium (III) oxide
- EC Number:
- 215-160-9
- EC Name:
- Chromium (III) oxide
- Cas Number:
- 1308-38-9
- Reference substance name:
- Chromium(III) oxide
- IUPAC Name:
- Chromium(III) oxide
- Reference substance name:
- Chromium(III) oxide
- IUPAC Name:
- Chromium(III) oxide
- Test material form:
- not specified
- Details on test material:
- Chromium(III) oxide
Constituent 1
Constituent 2
Constituent 3
Test animals / tissue source
- Species:
- rabbit
Results and discussion
In vivo
Results
- Irritation parameter:
- other: No reactions meeting the criteria for eye irritancy were observed.
- Remarks on result:
- other: Data from peer-reviewed assessment report
- Irritant / corrosive response data:
- No reactions meeting the criteria for eye irritancy were observed.
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information
- Conclusions:
- No eye irritation observed.
- Executive summary:
In a primary eye irritation study (according to OECD Guidelines 404 and 405) chromium(III) oxide was applicated to rabbit eyes. The substance caused no eye irritations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
