esterification product of 2-hydroxypropane-1,3-diyl-bis(2-methylprop-2-enoate) and 3-hydroxypropane-1,2-diyl-bis(2-methylprop-2-enoate) and diphosphorus pentoxide

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

October 31, 2001 - February 01, 2002

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

The study was conducted in accordance with OECD guidance and GLP guidelines. The method is restricted to test substances that do not undergo chemical reaction at temperatures below the boiling point. This study reports that the boiling point cannot be determined under conditions of the test, therefore this study is classified as reliable without restrictions.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2001

Report date:

2002

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Reference substance name:

1224866-76-5

Cas Number:

1224866-76-5

IUPAC Name:

1224866-76-5

Details on test material:

- Name of test material (as cited in study report): Glypho
- Substance type: pure active substance
- Physical state: liquid
- Stability under test conditions: Stable
- Storage condition of test material: Refrigeration at ca. 4°C

Results and discussion

Boiling point

Decomposition:

yes

Decomp. temp.:

240 - 280 °C

Any other information on results incl. tables

The boiling point of the CAS# 1224866-76-5 was measured using differential scanning calorimetry (DSC) and a capillary test method. In DSC, when the test substance undergoes a transition, such as boiling, it is indicated by a deviation from the base line of the heat-flow record. During boiling, heat is consumed and the deviation from the base line is in the endothermic direction. The boiling temperature of the test substance is evaluated from the DSC curve as the extrapolated onset temperature of the endothermic boiling peak. Reaction and/or decomposition was observed before boiling. In the capillary test method, the sample is filled into small glass tubes and boiling capillaries are inserted. The sample is steadily heated and is observed by direct visual observation for a current stream of bubbles evolving from the capillary which indicates boiling. This was repeated for four samples and no clear boiling point was detectable. The capillary test shows that at about 240 °C the sample changed its color from light yellow to dark brown which is due to the decomposition of the test sample.

The method is restricted to test substances that do not undergo chemical reaction at temperatures below the boiling point. This study reports that the boiling point cannot be determined under conditions of the test.

This study was conducted under two analyses (which includes a preliminary test):

The DSC-curve obtained during the preliminary test is shown in Figure 1. The sample was heated from 25 °C to 400 °C at a rate of 20 K/min. The DSC-curve shows no clear boiling point, rather an exothermic effect starting at 280 °C. The effect was due to reaction and/or decomposition of CAS# 1224866-76-5. After the experiment, the sample weight had decreased by 59% and the sample had carbonized and turned black. --> SEE ATT 1

To determine the heat effects more precisely, a test was performed using the capillary test. Four samples were used at a heating rate of 10 K/min between 100 °C and 300 °C. The effect of heating was visually determined to show a distinct color change indicating decomposition at 240 °C.

Applicant's summary and conclusion

Conclusions:

The boiling point of CAS# 1224866-76-5 could not be determined due to reaction and/or decomposition

Executive summary:

The boiling point of CAS# 1224866-76-5 was measured using differential scanning calorimetry (DSC) and in a capillary test method. In DSC, when the test substance undergoes a transition, such as boiling, it is indicated by a deviation from the base line of the heat-flow record. In the DSC curve, an exothermic peak is observed starting at 280 °C indicating the test substance has undergone a reaction and or decomposition. In the capillary test, which utilizes direct observation as the boiling point determinant, a color change occurred at about 240 °C at 986 hPa and no clear boiling point was detectable. It is determined that CAS# 1224866-76-5 does not boil at temperatures below its decomposition temperature.

This study was conducted in accordance with OECD TG 103 and is compliant with GLP standards. Reaction or decomposition was observed before boiling. The method is restricted to test substances that do not undergo chemical reaction at temperatures below the boiling point. The study reports that the boiling point cannot be determined under conditions of the test. Therefore this study is classified as reliable without restrictions.