Registration Dossier
Registration Dossier
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EC number: 700-945-5 | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Key Study:
The acute toxicity of the test material to the freshwater fish rainbow trout (Oncorhynchus mykiss) has been investigated and gave a 96 hour LL50 value of greater than 100 mg/L loading rate WAF. Correspondingly the No Observed Effect Loading (NOEL) rate was 100 mg/L loading rate WAF.
Supporting study:
In a limit test, the 96 hour LC50 was greater than 100 mg/L. During the 96 hour exposure period no toxic signs or mortality were observed.
Key value for chemical safety assessment
Additional information
Introduction
A study was performed to assess the acute toxicity of the test material to rainbow trout (Onchorhynchus mykiss). The method followed that described in the OECD Guidelines for Testing of Chemicals (1992) No. 203, “Fish Acute Toxicity Test” referenced as Method C.1 of Commission Directive 92/69/EEC.
Methods
Following a preliminary range finding study, fish were exposed in groups of ten to a Water Accommodated Fraction (WAF) of the test material at a single nominal loading rate of 100 mg/L for a period of 96 hours under semi-static test conditions. The number of mortalities and any sublethal effects of exposure in each test and control vessel were determined 3 and 6 hour after the start of exposure and then daily throughout the test until termination after 96 hours.
Results
The 96 hour LL50 based on nominal loading rates was greater than 100 mg/L WAF and correspondingly the No Observed Effect Loading rate was 100 mg/L. It was considered unnecessary and unrealistic to test at loading rates in excess of 100 mg/L.
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