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Physical & Chemical properties

Water solubility

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Description of key information

The water solubility of the test material has been determined to be 2.33 mg/l of solution at 20.0 ± 0.5° C.

Key value for chemical safety assessment

Water solubility:
2.33 mg/L
at the temperature of:
20 °C

Additional information

Method

The water solubility was investigated in a GLP-compliant study using the flask method according to the EU A.6 (2008) protocol. The experiment is deemed valid, conclusive and thus suitable for assessment without restrictions.

Based on the preliminary result, mixtures of test material and glass double-distilled water were added to three separate flasks. After addition of glass double-distilled water to the flasks, they were shaken at approximately 30°C and, after standing at 20°C for a period of not less than 24 hours, the contents of the flasks were centrifuged (6000 rpm for 15 minutes).

The pH of each solution was measured. The standard and sample solutions were analysed by GPC.

 

Validation for recovery of analysis was carried out at a nominal concentration of 1.00x10-3g/l and a percentage recovery of 96.0% (mean of 3) was obtained. Test solution concentrations have not been corrected for recovery of analysis.

 

Result

The water solubility of the test material has been determined to be 2.33mg/l of solution at 20.0 ± 0.5oC.