Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 689-188-9 | CAS number: 149343-84-0
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 18 May 1993 and 1 October 1993
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient - Shake Flask Method)
- Version / remarks:
- Method A8 of Commission Directive 92/ 69/ EEC (which constitutes Annex V of Council Directive 67/548/EEC)
- Deviations:
- yes
- Remarks:
- See "Any other information" for details
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- No further details specified in the study report.
- Analytical method:
- mass spectrometry
- Key result
- Type:
- Pow
- Partition coefficient:
- < 0
- Temp.:
- 24.5 °C
- pH:
- >= 5.9 - <= 6.1
- Details on results:
- The partition coefficient of JPR BLUE 100 (lot Number 303001) was determined to be less than 9.88e-7 at 24.5 ± 0.5 °C. Log10 Pow <-6.01.
The absorbances of the pair of standards associated with a particular sample were corrected to nominal concentration and the mean value taken prior to the calculation of the sample concentration. - Conclusions:
- The partition coefficient of JPR BLUE 100 (lot Number 303001) was determined to be less than 9.88e-7 at 24.5 ± 0.5 °C. Log10 Pow <-6.01.
- Executive summary:
A number of general physico-chemical properties of the compound JPR BLUE 100 (Lot Number 303001) have been determined at the request of the sponsor.
The Partition coefficient study complied with Method A8 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
The partition coefficient of JPR BLUE 100 (lot Number 303001) was determined to be less than 9.88e-7 at 24.5 ± 0.5 °C. Log10 Pow <-6.01.
Reference
The absorbance of the standard and sample solutions are detailed below:
ORGANIC PHASE |
|
Solution |
Absorbance (i.u.) |
Standard 0.101 mg/l Standard 9.99 x 10-2mg/l Sample 1 Sample 2 Sample 3 Sample 4 Sample 5 Sample 6 |
0.022 0.023 <0.022 <0.022 <0.022 <0.022 <0.022 <0.022 |
AQUEOUS PHASE |
|
Solution |
Absorbance (i.u.) |
Standard 10.1 mg/l Standard 9.99 mg/l Sample 1 Sample 2 Sample 3 Sample 4 Sample 5 Sample 6 Stock Solution A Stock Solution B |
0.497 0.492 0.499 0.512 0.514 0.509 0.507 0.499 0.498 0.499 |
Sample number |
Volume of n-octanol (ml) |
Volume of water (ml) |
Total weight (mg) |
n-octanol phase |
Water phase |
|||
Analysed concentration (mg/l) |
Total weight (mg) |
Analysed concentration (mg/l) |
Total weight (mg) |
pH |
||||
1 2 3 4 5 6 |
250 250 250 250 250 250 |
50 50 25 25 100 100 |
506 506 253 253 1.01 x 103 1.01 x 103 |
<1.00 x 10-2 <1.00 x 10-2 <1.00 x 10-2 <1.00 x 10-2 <1.00 x 10-2 <1.00 x 10-2 |
<2.50 x 10-3 <2.50 x 10-3 <2.50 x 10-3 <2.50 x 10-3 <2.50 x 10-3 <2.50 x 10-3 |
1.01 x 104 1.04 x 104 1.04 x 104 1.03 x 104 1.03 x 104 1.01 x 104 |
506 520 261 258 1.03 x 103 1.01 x 103 |
5.9 5.9 5.9 5.9 5.9 5.9 |
pH of stock solution = 5.9
pH of n-octanol saturated water = 6.1
Calculations
Sample number |
n-octanol/water volume ratio |
Partition coefficient |
Log10 Pow |
Mean partition coefficient |
1 2 |
5:1 |
<9.98 x 10-7 <9.63 x 10-7 |
<-6.01 <-6.02 |
<9.88 x 10-7 |
3 4 |
10:1 |
<9.59 x 10-7 <9.69 x 10-7 |
<-6.02 <-6.01 |
<9.69 x 10-7 |
5 6 |
5:2 |
<9.72 x 10-7 <9.88 x 10-7 |
<-6.01 <-6.01 |
<9.88 x 10-7 |
Mean = <9.88 x 10-7 Log10 Pow = <-6.01
Description of key information
The partition coefficient of JPR BLUE 100 (lot Number 303001) was determined to be less than 9.88e-7 at 24.5 ± 0.5 °C. Log10 Pow <-6.01.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0
- at the temperature of:
- 24.5 °C
Additional information
A number of general physico-chemical properties of the compound JPR BLUE 100 (Lot Number 303001) have been determined at the request of the sponsor.
The Partition coefficient study complied with Method A8 of Commission Directive 92/69/EEC (which constitutes Annex V of Council Directive 67/548/EEC).
The partition coefficient of JPR BLUE 100 (lot Number 303001) was determined to be less than 9.88e-7 at 24.5 ± 0.5 °C. Log10 Pow <-6.01.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
