Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 604-580-1 | CAS number: 147256-33-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Microbial toxicity is unlikely to occur in the range of water solubility (< 0.05 mg/L)
Key value for chemical safety assessment
Additional information
In accordance with Annex VIII, column 2,9.1.4 of Regulation (EC) No. 1907/2006, activated sludge respiration inhibition testing is not required since the substance is highly insoluble in water. Additionally, Fatty acids, C18-unsatd., dimers, mixed esters with oleic acid and trimethylolpropane (CAS No. 147256 -33 -5) is readily biodegradable, which indicate that the substance will not cumulate in the environment and is not inhibitory to activated sludge microorganisms up to the applied test concentrations in the biodegradation studies.Based on these mitigating factors, it is unlikely that microbial toxicity occurs. This assumption is confirmed by a supporting study; however, this study does not meet important criteria of today standard methods and thus is not sufficient to cover this endpoint (Guhl, 1991). In a respiration inhibition test with Pseudomonas putida performed according to GLP and DIN guideline 38412, part 27, no inhibition was observed up to a test concentration of 10,000 mg/L during a test period of 30 minutes resulting in a NOEC ≥ 10000 mg/L.
Based on this information Fatty acids, C18-unsatd., dimers, mixed esters with oleic acid and trimethylolpropane (CAS No. 147256-33-5) implies low toxicity to activated sludge microorganisms.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
