Registration Dossier
Registration Dossier
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EC number: 236-690-7 | CAS number: 13464-97-6
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- other: assessment of available data
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Assessment of available data only.
- Justification for data waiving:
- other:
Data source
Materials and methods
Test material
- Reference substance name:
- Hydrazine mono-nitrate
- IUPAC Name:
- Hydrazine mono-nitrate
- Reference substance name:
- Hydrazinium nitrate
- EC Number:
- 236-690-7
- EC Name:
- Hydrazinium nitrate
- Cas Number:
- 13464-97-6
- Molecular formula:
- H4N2.HNO3
- IUPAC Name:
- hydrazinium nitrate
Constituent 1
Constituent 2
Results and discussion
Main ADME resultsopen allclose all
- Type:
- absorption
- Results:
- Sensitisation observed, indicating absorption occurs via the skin.
- Type:
- distribution
- Results:
- No data
- Type:
- metabolism
- Results:
- No data.
- Type:
- excretion
- Results:
- No data
Metabolite characterisation studies
- Metabolites identified:
- not specified
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information): no data
Hydrazine mono-nitrate is absorbed via the dermal route. - Executive summary:
No specific data on toxicokinetics are available. Interpretation of the existing toxicological data indicates that hydrazine mono-nitrate is absorbed via the skin, due to the sensitisation observed in this category of substances as exemplified by the classification (hydrazine salts). The elucidation of absorption via the oral and inhalatory routes, distribution, metabolism and excretion has not been possible due to waiving of data.
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