Registration Dossier
Registration Dossier
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EC number: 435-680-1 | CAS number: -
Respiratory sensitisation
Administrative data
- Endpoint:
- respiratory sensitisation, other
- Remarks:
- Experience with the chemical class of the substance and from observations of workers.
- Type of information:
- other: Experience with the chemical class of the substance and from observations of workers.
- Adequacy of study:
- other information
- Study period:
- 2018
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Experience with the chemical class of the substance and from observations of workers.
Data source
Reference
- Reference Type:
- other: Experience at the registrant
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Experience with the chemical class of the substance and from observations of workers.
- GLP compliance:
- no
Test material
- Reference substance name:
- -
- EC Number:
- 435-680-1
- EC Name:
- -
- Cas Number:
- 24701-69-7
- Molecular formula:
- C9H12N2O4S (Hill formula) C9H12N2O4S (CAS formula)
- IUPAC Name:
- (6R,7R)-7-amino-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- Test material form:
- solid: particulate/powder
- Remarks:
- migrated information: powder
- Details on test material:
- Name: 7-AMCA
Chemical name: 7-Amino-3-methoxy-cefalosporanic acid
Molecular formula: C9H12N2O4S
CAS No.: 24701-69-7
Supplier: Sponsor
Batch No.: 36423006
Certificate of analysis: Available
Purity: 90.1 % on anhydrous basis (HPLC)
Water content: 0.3 %
Solubility: In water 0.1 g/L at 20 °C
In methanol 0.05 g/L
Appearance: Yellowish powder
Conditions of storage: Refrigerator, in the dark. Protected from moisture
Stability: Stable over ca. 6 months under conditions of storage. Stable over several weeks at room temperature
Date of expiry: October 2000
Constituent 1
Test animals
- Species:
- other: Humans
Results and discussion
Applicant's summary and conclusion
- Interpretation of results:
- Category 1 (respiratory sensitising) based on GHS criteria
- Conclusions:
- Experience with the chemical class of the substance and from observations of workers advises to classify the substance as Resp.Sens. 1.
- Executive summary:
Experience with the chemical class of the substance and from observations of workers advises to classify the substance as Resp.Sens. 1.
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