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EC number: 413-110-2
CAS number: 135861-56-2
the substance is not considered to be toxic or harmful after oral and
dermal exposure, acute (systemic) DNELs do not need to be derived. As
the substance is not considered to be irritating to skin and eyes, acute
(local) DNELs do not need to be derived.
signs of unspecific toxicity (effects on body weight gain) were observed
at a dose higher than the limit dose in a 90-d study in rats. The test
substance does not pose any specific risk following repeated oral
The results of the OECD 421 study (NOEL = 1000 mg/kg bw
nominal) did not indicate adverse effects on reproductive organs or
tissues and no concern exists in relation with reproductive toxicity. In
addition, an OECD 415 (1-gen study) conducted with a structural analogue
also did not indicate any adverse effects.
the substance is not considered to be hazardous with respect to
long-term effects, long term (systemic) DNELs do not need to be derived. As
local effects were not observed in the repeated dose toxicity study,
long term (local) DNELs do not need to be derived.
substance is not readily available to consumers, as there is very little
potential for the substance to be released from the polymers once it has
been consumed in the polymer manufacturing process. Therefore, DNELs for
the general population do not need to be derived.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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