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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

The EC50 (growth rate for diallyldimethylammonium chloride has been established at >100 mg/L based on 3 GLP studies on 2 different strains of unicellular green algae. The ErC10 for freshwater algae in a long-term study (96 hours) was 57 mg/L.

Key value for chemical safety assessment

EC50 for freshwater algae:
100 mg/L
EC10 or NOEC for freshwater algae:
57 mg/L

Additional information

The toxicity of diallyldimethylammonium chloride to unicellular green algae has been tested recently in 3 GLP studies on 2 recommended test species: Desmodesmus subspicatus (2 studies) and Pseudokirchneriella subcapitata (1 study).

In only one of these studies (Vreyenhof, 2009) was the EC50 for growth rate at 72 hours under 100 mg/L (91 mg/L). This value, however, was less than 10% below 100 mg/L and its upper 95% confidence limit was 100 mg/L. At 96 hours the value was 120 mg/L showing decreasing toxicity with time and supporting the upper 95% CL value.

Taking the above into account along with the LC50/fish of 420 mg/L, the EC50/daphnia of >100 mg/L and the EC0/bacteria of >1000 mg/L, the EC50 growth rate of diallyldimethylammonium chloride for unicellular green algae has been established at >100 mg/L.

At 96 hours the ErC10 for the freshwater algae Desmodesmus subspicatus was 57 mg/L.