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EC number: 231-900-3
CAS number: 7778-18-9
Data is available on the acute toxicity of calcium sulfate to fish. The
results from these studies demonstrate that calcium sulfate is not
acutely toxic at the limit of its solubility in water.
A reliable GLP guideline study was performed which assessed the acute
toxicity of calcium sulfate dihydrate (NIER, 2003) to Oryzias latipes in
a limit test. The 96 h LC50 for calcium sulfate dihydrate was found to
be >100 mg/L, which is equivalent to >79 mg/L for calcium sulfate
anhydrous. No mortalities or adverse effects were noted at this
Supporting studies are also available from literature. Trama (1995)
tested the acute toxicity of a saturated solution of calcium sulfate at
20 °C to Lepomis macrochirus (bluegill sunfish). No
significant mortalities were observed at the concentration tested (2980
ppm). Therefore, the 96 h LC50 of calcium sulfate to bluegill sunfish
was >2980 mg/L.
Mount et al (1997) investigated the acute toxicity of calcium sulfate to Pimephales
promelas (fathead minnow). The 96 h LC50 for calcium sulfate was
Wallen et al (1957) cited a 96 h LC50 of calcium sulfate to Gambusia
affinis >56,000 mg/L. The LC50 value is therefore greater than the
maximum solubility of calcium sulfate in water.
Using a weight of evidence approach, the acute toxicity of calcium
sulfate to fish is greater than the highest concentration tested and is
greater than the maximum solubility of calcium sulfate in water.
Calcium sulfate showed no short-term toxicity to fish and is not acutely
toxic to fish at the limit of its water solubility.
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