Refractories, fibers, aluminosilicate

Endpoint summary

Additional information

The regulatory gene mutation and chromosome aberation tests conducted on RCF indicate that this material is not genotoxic. This is supported by the conclusions of the DECOS report, which states that RCF is non-genotoxic. The SCOEL report concludes that any genotoxic effects are secondary to the production of reactive oxygen species.

Short description of key information:
These fibres were negative in bacterial mutation studies and in vitro micronucleus test

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

These fibres produced clear and unequivocally negative results in in vitro testing.