Registration Dossier
Registration Dossier
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EC number: 692-448-4 | CAS number: 170621-28-0
Endpoint summary
Administrative data
Description of key information
LL50 (96 h)> 100 mg/L (nominal, loading rate) (OECD 203, Danio rerio). Measured concentration of Al and V were 0.31 mg/L and 0.30 mg/L, respectively.
NOELR (14 d, growth rate) < 100 mg/L (nominal, loading rate) (OECD 204, Gobiocypris rarus). Measured concentration of Al, V, and Mg were 1.74 mg/L, 0.588 mg/L, and 15.3 mg/L.
EL50 (48 h, immobolisation) = 15 mg/L (nominal, loading rate) (OECD 202, Daphnia magna). Measured concentration of Al and V are 0.18 - 0.54 mg/L (geom. mean) and 0.04 - 0.14 mg/L (geom. mean), respectively.
NOELR (21 d) = 0.160 mg/L (nominal, loading rate) (OECD 211, Daphnia magna). Corresponding to the time-weighted mean measured concentrations of Al, V and Mg of 0.00833, 0.00213 and 8.64 mg/L, respectively.
EL50 (72h, growth rate) > 100 mg/L (nominal, loading rate) (OECD 201, Desmodesmus subspicatus). NOELR (72h, growth rate) = 46 mg/L (nominal, loading rate) (OECD 201,Desmodesmus subspicatus). The measured concentrations for Al were 0.06 - 0.48 mg/L (geom. mean).
EC50 (3h) > 1000 mg/L (nominal) (OECD 209, activated sludge)
Additional information
Short-term and chronic studies for three different trophic levels (fish, invertebrates and algae) are available to evaluate the aquatic toxicity of aluminium magnesium vanadium oxide.
As the substance has shown to be poorly soluble in water (< 0.1 mg/L), it can be assumed that under environmental conditions in aqueous media, the components of the substance will be present in a bioavailable form only in minor amounts, if at all.
Due to the poor solubility of the test item all test organisms were exposed to filtered test solutions. Thus, effects of the substance towards fish, Daphnia, and algae are reported on a nominal basis as loading rates. The following results were obtained: for fish both the LL50 (96 h) and the NOELR (14 d) were > 100 mg/L, for Daphnia the EL50 (48 h) and NOELR (21 d) were 15 mg/L and 0.16 mg/L, respectively, for algae the EL50 (72 h) and NOELR (72 h) were > 100 mg/L and 46 mg/L, respectively. In all studies analytical measurement of concentrations was conducted. Measured concentrations of magnesium, aluminium and vanadium are presented in the studies and recoveries reported. Measured concentrations were generally much lower than nominal value, however, recoveries demonstrated stability of the substance over the course of the studies.
In a study performed with activated sludge, the test substance had no effect on the respiration rate of the microorganisms. Inhibition at the highest rate tested did not rise above 8%, therefore the 3 hours EC50 and NOEC are reported as > 1000 mg/L and 320 mg/L, respectively.
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