Registration Dossier
Registration Dossier
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EC number: 203-581-0 | CAS number: 108-42-9
Acute Toxicity: other routes
Administrative data
- Endpoint:
- acute toxicity: other routes
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Test method and results insufficient described
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 982
- Report date:
- 1982
Materials and methods
- Principles of method if other than guideline:
- The intraperitoneal LD50 (24 hours) was determined on male NMRI mice in a pre-test for a micronuleus test
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3-chloroaniline
- EC Number:
- 203-581-0
- EC Name:
- 3-chloroaniline
- Cas Number:
- 108-42-9
- Molecular formula:
- C6H6ClN
- IUPAC Name:
- 3-chloroaniline
- Reference substance name:
- m-chloroaniline
- IUPAC Name:
- m-chloroaniline
- Test material form:
- other: liquid
- Details on test material:
- 3-chloroaniline ca. 98% - EGA Chemie
Constituent 1
Constituent 2
Test animals
- Species:
- mouse
- Strain:
- NMRI
- Sex:
- male
Administration / exposure
- Route of administration:
- intraperitoneal
- Vehicle:
- not specified
- Doses:
- no data
- No. of animals per sex per dose:
- no data
- Control animals:
- not specified
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 216 mg/kg bw
- Based on:
- test mat.
Any other information on results incl. tables
The intraperitoneal LD50 = 216 mg/kg bw (confidence level: 137 - 343 mg/kg bw)
Applicant's summary and conclusion
- Executive summary:
The intraperitoneal LD50 (24 hours) was determined on male NMRI mice in a pre-test for a micronuleus test. A LD50 = 216 mg/kg bw was found.
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