Registration Dossier
Registration Dossier
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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 200-831-0 | CAS number: 75-01-4
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: In this record a summary of a report on accidental eye exposure to liquid vinyl chloride is provided. The study has been published in peer-reviewed literature and is considered adequate for assessment.
Data source
Reference
- Reference Type:
- publication
- Title:
- Chemical Burns of the Human Cornea
- Author:
- McLaughlin, R.S
- Year:
- 1 946
- Bibliographic source:
- Am. J. Ophthalmol., Vol. 29, 1355 - 1362
Materials and methods
- Study type:
- poisoning incident
- Endpoint addressed:
- eye irritation
- Principles of method if other than guideline:
- Case report
- GLP compliance:
- no
Test material
- Reference substance name:
- Chloroethylene
- EC Number:
- 200-831-0
- EC Name:
- Chloroethylene
- Cas Number:
- 75-01-4
- Molecular formula:
- C2H3Cl
- IUPAC Name:
- chloroethene
Constituent 1
Method
- Type of population:
- general
Results and discussion
- Results of examinations:
- Chemical burns of the cornea after spray accident with liquid vinyl chloride (presumably due to hypothermal effect). Treatment with denuding technique. Prompt healing with 48 h.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
