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EC number: 205-087-0 | CAS number: 133-06-2
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25 May to 19 June 1987
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: U.S.-EPA Test Method CG-1400: Partition Coefficient (n-Octanol/Water)
- Version / remarks:
- August 1982
- GLP compliance:
- yes
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- Appearance: white solid crystals
Purity: 98.9%
Batch no.: S-13 (518)
Supplied by Makhteshim Chemical Works Ltd. on May 1987 - Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 372
- Temp.:
- 25 °C
- Remarks on result:
- not measured/tested
- Remarks:
- pH value
- Conclusions:
- The results showed that captan at 25°C has a partition coefficient Kow of 372 (S.D. = 27.2).
- Executive summary:
The partition coefficient (Kow ) of captan in n-octanol and water was determined by allowing captan to equilibrate between water-saturated n-octanol and n-octanol-saturated water and measuring the concentrations of captan in the two phases by high performance liquid chromatography (HPLC) and calculating the (Kow)
The test was carried out at two captan concentrations C = 1.9 x I0-3 mol/L and C1 = 1.9 x 10-4 mole/L, and at a n-octanol/water ration of 1:60.
The results showed that captan at 25°C has a partition coefficient of 372 (S.D. = 27.2).
Reference
Table III. Experimental data and the captan partition coefficient results
Working Concentration | Exp. No. | Octanol/water ratio | Captan conc. in octanol (mole/L) | Captan conc. in water (mole/L) | Partition coefficient (Kow) |
C | A1 | 1:60 | 1.57x10-3 | 4.26x10-6 | 369 |
A2 | 1:60 | 1.55x10-3 | 4.60x10-6 | 337 | |
A3 | 1:60 | 1.54x10-3 | 4.00x10-6 | 385 | |
|
|
|
|
| Mean: 364 S.D.: 24.4 |
C1 | B1 | 1:60 | 1.73x10-4 | 4.80x10-7 | 360 |
B2 | 1:60 | 1.69x10-4 | 4.63x10-7 | 365 | |
B3 | 1:60 | 1.60x10-4 | 3.83x10-7 | 418 | |
|
|
|
|
| Mean: 381 S.D.: 32.1 |
| Mean: | 372 | |||
Standard deviation: | 27.2 | ||||
% standard deviation: | 7.3 | ||||
Description of key information
Partition coefficient for captan was determined to be kow 372, log Pow 2.57 at 25°c.
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 2.57
- at the temperature of:
- 25 °C
Additional information
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