Registration Dossier
Registration Dossier
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EC number: 201-163-2 | CAS number: 78-97-7
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Peer reviewed data base
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 993
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 401 (Acute Oral Toxicity)
- GLP compliance:
- yes
Test material
- Reference substance name:
- Lactonitrile
- EC Number:
- 201-163-2
- EC Name:
- Lactonitrile
- Cas Number:
- 78-97-7
- Molecular formula:
- C3H5NO
- IUPAC Name:
- 2-hydroxypropanenitrile
- Details on test material:
- 2-Hydroxypropanenitrile
Purity: 92.3 %
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Crj: CD(SD)
- Sex:
- male
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- LD50
- Effect level:
- 31 mg/kg bw
Any other information on results incl. tables
RS-Freetext:
Mortality
LD50 = 31.0 (mg/kg) for male
LD50 = 41.1 (mg/kg) for female
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
