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EC number: 939-060-6
CAS number: -
In a sensitisation toxicity study the test item Initiator 94 was
formulated in DMSO.
A local lymphnode assay was performed. Concentrations of the test item
of 0 %, 2.5%, 5 % and 10 %. in 25 µl DMSO/ear/day were applied to the
dorsal surface of the ears of groups of 4 female mice on 3 consecutive
days. The highest concentration was the highest level that could be
achieved with an applicable formulation.
The animals did not show any signs of systemic toxicity. The test item
was not a skin sensitiser.
On days 2 -4 the animals treated with a test item concentration of 10 %
showed an erythema of the ear skin (score 1). Animals treated with lower
test item concentrations did not show any signs of local skin irritation.
Initiator 94 is irritating to the skin when applied in concentrations of
10% or higher.
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