Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 248-096-5 | CAS number: 26896-48-0
Endpoint summary
Administrative data
Description of key information
TCD Alcohol DM was determined to be not readily biodegradable.
In a surface water simulation test (OECD TG 309) with river water (SPM 13 mg DW/L), TCD Alcohol DM was first rapidly oxidized to an isomeric mixture of TCD Monoacids (apparent first order DT50 0.121 d - 0.235 d at 20 µg/L initial concentration), followed by a rapid further oxidation to the TCD Diacids under steady decrease of the TCD Monoacids. The concentration of the TCD Diacids remained in a plateau to the end of the study.
Additional information
In the reliable key study, octahydro-4,7-methano-1H-indenedimethanol (TDC-Alcohol DM) was assessed for ready biodegradability in the CO2 -evolution test according to OECD 301B (LAUS, 2015). No degradation was observed within 28 days (0% within both replicates). Therefore, the test item must be considered to be not readily biodegradable, and no indication for inherent biodegradability is given by these results. No inoculum toxicity was observed at a concentration of 29.0 mg/L.
This is supported by a MITI (I)-Test with TCD-Alcohol DM, following OECD TG 301 C. No relevant degradation (1 %) was observed and the compound assessed to be not biodegradable (NITE, 2004).
The simulation degradation testing (OECD TG 309; Noack, 2021) with river water (SPM 13 mg DW/L) performed at 12 °C over 65 days on cold test item TCD Alcohol DM had the following results: Transformation of TCD Alcohol DM started directly after application. Already after two days, the detected concentration was < 10 % of the applied concentration.
The TCD Alcohol DM isomers 1, 2 and 3 were first oxidized to an isomeric mixture of TCD Monoacids followed by further oxidation to the TCD Diacids under steady decrease of the TCD Monoacids. The concentration of the TCD Diacids remained in a plateau to the end of the study.
Apparent first order DT50 for TCD Alcohol DM: 0.121 d - 0.235 d (20 µg/L initial conc.); 0.585 d - 0.669 d (100 µg/L initial conc.).
A study on sediment simulation testing is scientifically not necessary: TCD Alcohol DM does not have a high potential for adsorption (log Kow < 3 IUCLID Sect. 4.7, low estimated Koc of 16.8, IUCLID Sect. 5.4.1). Based on the valid simulation test on degradation in surface water (OECD TG 309; Noack, 2021), TCD Alcohol DM is rapidly transformed to the dicarboxylic acid derivative. Any losses due to adsorption could reliably be excluded based on a mass balance of ca. 100 %. No relevant further information could be expected from additional simulation testing with sediment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
