Registration Dossier
Registration Dossier
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EC number: 248-096-5 | CAS number: 26896-48-0
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
In a valid activated sludge respiratory inhibition test according to OECD TG 209, the EC50 of TCD Alkohol DM was determined to be 2400 mg/L, the NOEC was identified at 440 mg/L.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 440 mg/L
Additional information
To assess the toxicity of TCD Alkohol DM to microorganisms, a valid activated sludge respiratory inhibition study according to OECD test guideline 209 is available (Muckle/LAUS GmbH, 2010). In this study activated sludge was exposed to 12 concentrations of TCD Alkohol DM between 200 and 11000 mg/L. After 3 hours, the rate of oxygen consumption and percentage of respiratory inhibition was determined.
Controls showed the expected values. Validity criteria were met. Above a test substance concentration of about 2000 mg/L, respiratory inhibition levelled off and did not exceed 59% even at concentrations up to 11000 mg/L. This may be due to a limited water solubility of the test substance.
The EC50 was determined to be 2400 mg/L (95% CL 1600 - 4400 mg/L), the NOEC was identified at 440 mg/L (Muckle/LAUS GmbH, 2010).
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