Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Study period:
June 2011
Data waiving:
study technically not feasible
Justification for data waiving:
other:

Data source

Reference
Reference Type:
other: Expert Statement
Title:
Unnamed
Year:
2011
Report date:
2011

Materials and methods

GLP compliance:
no
Partition coefficient type:
octanol-water

Test material

Constituent 1
Reference substance name:
Absorbent N grade A
IUPAC Name:
Absorbent N grade A
Details on test material:
- Name of test material (as cited in study report): Absorbent N grade A
- Substance type: UVCB
- Physical state: Brown liquid
- Stability under test conditions: months
- Storage condition of test material: room temperature, in the dark

Results and discussion

Applicant's summary and conclusion

Conclusions:
Due to the state of the test item of “ABSORBENT N grade A” as complex compound so called UVCB (substances of Unknown or Variable composition, Complex reaction products or Biological materials) a determination of the Partition Coefficient (n-octanol/water) according to OECD 107 and OECD 117 is not possible.
Executive summary:

The test item is a complex compound which needs to be described as UVCB. It consists of a large amount of different components as shown in the chromatograms provided by the client. In an UVCB substance it is not distinguished between main constituents and impurities, due to the large amount of constituents and the relatively low percentage of each of them. Furthermore the components show inhomogeneous properties in terms of their solubility. These properties and the great number of components make a determination of the Partition Coefficient (n-octanol/water) according to OECD 107 and OECD 117 as well as a profound estimation through calculation of the partition in an octanol matrix impossible.

Due to the specified problems described above a determination of the partition coefficient according to OECD 107 and OECD 117 is technically not possible.