Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Key value for chemical safety assessment

Acute toxicity: via oral route

Link to relevant study records
Reference
Endpoint:
acute toxicity: oral
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reason / purpose for cross-reference:
read-across source
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
>= 486 - <= 516 mg/kg bw
Based on:
other: calculated for target substance to be registered
Remarks on result:
other: see below "overall remarks"
Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
500 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Acute toxicity: via dermal route

Link to relevant study records
Reference
Endpoint:
acute toxicity: dermal
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reason / purpose for cross-reference:
read-across source
Key result
Sex:
male/female
Dose descriptor:
LD50
Effect level:
678 mg/kg bw
Based on:
other:
Remarks:
calculated for target substance to be registered
Remarks on result:
other: see below "overall remarks"
Endpoint conclusion
Endpoint conclusion:
adverse effect observed
Dose descriptor:
LD50
Value:
678 mg/kg bw

Additional information

Justification for classification or non-classification

The substance is classified for acute oral toxicity in Category 4 and for acute dermal toxicity in Category 3 according to Regulation 1272/2008.

Non-classification for acute inhalation toxicity is justified because of the very low vapour pressure of the substance.